Engine Biosciences raises $10 million in Southeast Asia’s largest institutional seed spherical

Fundings and Exits



Life sciences startups in Asia are getting one other enhance with the $10 million funding in Engine Biosciences — a biotech firm that’s making use of machine studying to genomics for drug discovery.

With its headquarters in each Singapore and San Francisco, the corporate has managed to draw some spectacular buyers from each the U.S. and Asia. The spherical was co-led by Danhua Enterprise Capital and 6 Dimensions Capital, with extra participation from WuXi AppTec, EDBI, Pavilion Capital, Baidu Ventures, WI Harper and Nest.Bio Ventures.

Based by a who’s who of researchers, together with Massachusetts Institute of Expertise professors Timothy Lu and Jim Collins; Mayo Clinic Assistant professor Hu Li; and College of California San Diego assistant professor, Prashant Mali, Engine is leveraging specialists in artificial biology and drug discovery to create a brand new method to construct and take a look at novel medicines.

In response to a press release, the corporate will use the cash to proceed growing its drug discovery platform, develop the chief and scientific workforce in Singapore and the U.S. and start pre-clinical research internally and with companions — which already embody undisclosed analysis establishments and an unnamed Fortune 500 firm right here within the U.S.

Combining parallel organic experimentation with machine studying to develop therapies, Engine is constructing a system for brand spanking new drug discovery that’s sooner and cheaper to check than current methodologies, the corporate claims.

“The biopharmaceutical trade wants higher approaches for R&D to ship therapies to sufferers in want sooner. Legacy approaches imply that in lots of circumstances, we nonetheless have a weak understanding of what drives illness and correspondingly, easy methods to deal with or stop it,” mentioned Engine Biosciences co-founder and CEO Jeffrey Lu, in a press release. “Engine’s data-driven platform permits researchers to not solely uncover the essential gene interactions underlying ailments, but in addition take a look at therapies that particularly goal these interactions in a sooner, cheaper and extra exact trend than at present potential.”

Up to now, the expertise is getting used for drug repositioning, which creates new functions for current medicine; goal discovery, which seems at potential organic components for illness; precision medication by way of concentrating on particular genes; and pathway evaluation.

Already the corporate has seen proof-of-concept successes round remedies for most cancers, neurodegenerative, autoimmune issues and pores and skin issues.

“The dearth of perception into advanced and multi-factorial organic processes inside cells contributes to the excessive failure fee throughout the drug growth cycle. Engine Biosciences has pioneered a brand new method to deal with this by producing novel knowledge and insights which might be extremely related to the organic course of,” mentioned Dr. Leon Chen, founding CEO of 6 Dimensions Capital and a member of Engine’s board of administrators. “We anticipate the corporate’s AI platform will result in insightful data in advanced ailments’ pathways that was not beforehand potential utilizing conventional moist lab-centric biology analysis and we’re excited to assist the workforce with our funding.”



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